Table 1 Demographic data of the study patients.

	Patients treated with methadone	Patients treated with buprenorphine	p Value
n	407	43	––
Sex (F:M)	107:300	9:34	0.4569
Mean (SD) age (years)	41.3 (8.3)	38.0 (7.6)	0.0145
Treatment period (years) (median (10th and 90th percentile))	7 (0.5;20)	1 (0.02;4)	<0.0001
Methadone dose (mg) (median (10th and 90th percentile))	100 (50;235)	––	––
Buprenorphine dose (mg) (mean (10th and 90th percentile))	––	5.4 (0.6;12)	––
Patients with cocaine use past week	76 (18.7%)	5 (10.6%)	0.2528
Patients with illicit opioid use past week	121 (29.7%)	16 (34.0%)	0.3108
Patients with cannabis use past week	243 (59.7%)	19 (40.4 %)	0.0497
Patients with illicit benzodiazepine use	88 (21.6%)	5 (10.7%)	0.1238