Table 2 Coeliac disease and risk of later vascular disease.

Outcome	Overall estimates	Adjusted for DM*	Individuals with DM* excluded	Vascular disease is main diagnosis†‡	Vascular disease is main diagnosis†‡	Comparison with inpatient reference individuals	First year of follow‐up included
	HR§, 95% CI	AHR§, 95% CI	HR§, 95% CI	HR§, 95% CI	HR§, 95% CI	HR§, 95% CI	HR§, 95% CI
Myocardial infarction	1.27, 1.09 to 1.48	1.26, 1.08 to 1.47	1.23, 1.03 to 1.47	1.18, 1.00 to 1.40	1.19, 1.00 to 1.41	0.93, 0.77 to 1.18	1.27, 1.10 to 1.47
Angina pectoris	1.46, 1.25 to 1.70	1.44, 1.23 to 1.68	1.37, 1.15 to 1.63	1.36, 1.14 to 1.64	1.36, 1.41 to 1.64	0.98, 0.81 to 1.18	1.42, 1.23 to 1.65
Heart failure	1.41, 1.22 to 1.62	1.43, 1.24 to 1.65	1.48, 1.26 to 1.74	1.45, 1.20 to 1.76	1.44, 1.18 to 1.75	0.79, 0.68 to 0.92	1.56, 1.38 to 1.78
Brain haemorrhage	1.40, 1.05 to 1.88	1.42, 1.06 to 1.90	1.34, 0.97 to 1.83	1.37, 1.01 to 1.86	1.33, 0.96 to 1.83	1.26, 0.87 to 1.83	1.63, 1.24 to 2.13
Ischaemic stroke	1.35, 1.14 to 1.60	1.34, 1.13 to 1.59	1.38, 1.14 to 1.66	1.37, 1.14 to 1.64	1.38, 1.15 to 1.66	0.92, 0.76 to 1.12	1.37, 1.17 to 1.60

AHR, adjusted hazard ratio; DM, diabetes mellitus.

First year of follow‐up has been excluded in all the above analyses except when otherwise noted.

*DM, type 1 or type 2.

†HR for vascular disease listed as the main diagnosis. All other analyses refer to vascular disease listed as main or secondary diagnosis.

‡Analyses restricted to individuals with coeliac disease diagnosed in adulthood (and reference individuals entering the study in adulthood).

§Estimates derived from Cox's regression.