Table 3 ORs and 95% CI for the expression of Mib1, Cdx2, hTERT and pro‐caspase 3 in the three glandular compartments, according to the dependent ordinal variables considered.

Glandular compartment	Mib1	Cdx2	hTERT	Pro‐caspase 3
Superficial/foveolar (zone 3)	8.8 (3.3 to 23.0)	2.3 (2.0 to 5.2)	33.1 (6.7 to 163.9)	7.8 (3.6 to 16.8)
Proliferative (zone 1)	7.4 (3.6 to 15.0)	8.6 (4.1 to 18.0)	8.8 (3.0 to 11.2)	3.2 (1.8 to 5.7)
Coils (zone 2)	4.4 (2.3 to 8.5)	3.3 (2.1 to 5.0)	4.1 (1.9 to 8.8)	2.0 (1.1 to 3.4)

Values are given as OR (95% CI).

For all but one (Cdx2 in glandular coils 2 =  p<0.01), the reported ORs were significant at a p value of <0.001.

Dependent ordinal variables considered were intestinal metaplasia, indefinite for non‐invasive neoplasia and low‐grade non‐invasive neoplasia.