Table 2 Summary of immunohistochemical and Epstein–Barr virus RNA in‐situ hybridisation results in nasal natural killer/T‐cell lymphomas.
Case | CD3 | CD4 | CD8 | CD79a | CD56 | CD57 | CD3e | TIA‐1 | EBER (%)* | Type | F/“f” | I/“i” | XhoI |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ++ | +/− | ++ | −† | − | − | ++ | ++ | 80 | 1 | F | “i” | Loss |
2 | ++‡ | − | − | −† | ++ | − | ++ | ++ | 90< | 1 | F | NA | Wild type |
3 | −† | − | −§ | −† | ++ | − | −§ | ++ | 90< | 1 | F | NA | Loss |
4 | ++‡ | −† | −† | −† | ++ | −§ | ++ | ++ | 80 | NA | “f” | NA | NA |
5 | ++ | −§ | ++ | −† | − | −† | + | ++ | 70 | 1 | F | “i” | Loss |
6 | ++‡ | − | −† | − | ++ | −§ | ++ | ++ | 0 | NT | NT | NT | NT |
7 | −§ | − | −§ | −† | ++ | NT | ++ | ++ | 0 | NT | NT | NT | NT |
8 | −§ | − | + | − | + | NT | ++ | ++ | 90< | 1 | F | “i” | Loss |
9 | +‡ | − | ++ | −† | − | NT | ++ | ++ | 70 | 1 | F | “i” | Wild type |
EBER, Epstein–Barr virus‐encoded small RNA; NA, not amplified; NT, not tested.
*In‐situ hybridisation results were expressed as number of positive cells per medium‐powered field (×200). Cases were considered positive when a positive signal was observed in ⩾10% of the tumour cells.
†Background was also reacted.
‡Cytoplasmic expression was observed.
§Positive for reactive cells but not for neoplastic cells.