Table 2 Descriptive statistics of nuclear insulin receptor substrate 1 and oestrogen receptor α in all samples.
| Normal epithelium | Benign tumours | ||||
|---|---|---|---|---|---|
| ERα | IRS‐1 | ERα | IRS‐1 | ||
| Mean ( SE) | 21.7 (6.1) | 2.3 (0.6) | 23.4 (4.2) | 23 (4.5) | |
| Median (range) | 10.5 (0–60) | 1.6 (0–7) | 20.5 (0–70) | 20.5 (0–60) | |
| Ductal Carcinoma | G2 | G3 | |||
|---|---|---|---|---|---|
| ERα | IRS‐1 | ERα | IRS‐1 | ||
| Mean (SE) | 51.8 (10.1) | 23.4 (7.1) | 6.2 (3.4) | 4.1 (1.8) | |
| Median (range) | 65 (0–92) | 11 (0–72) | 0 (0–40) | 0 (0–20) | |
| Lobular carcinoma | G2 | G3 | |||
|---|---|---|---|---|---|
| ERα | IRS‐1 | ERα | IRS‐1 | ||
| Mean (SE) | 64.8 (11.3) | 32 (9.7) | 26.7 (8.9) | 30.7 (4.7) | |
| Median (range) | 80 (0–90) | 35 (0–80) | 15 (0–80) | 33.5 (0–52) | |
ERα, oestrogen receptor α; IRS‐1, insulin receptor substrate 1.
The mean (SE) expression with median (range) values for nuclear IRS‐1 and ERα in all specimens (ERα‐positive and ERα‐negative) is given. Samples of cancer of ductal and lobular origin were grouped separately into G2 and G3 populations.