Table 6 Correlations between cytoplasmatic insulin receptor substrate 1 and selected clinicopathological features in oestrogen receptor α‐positive tumours.
| Ductal | Lobular | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 0 | 1+ | 2+ | 3+ | 0+ | 1+ | 2+ | 3+ | ||
| ERα | r | — | 0.978 | 0.637 | 0.987 | — | — | 0.198 | −0.029 |
| P Value | 0.025 | 0.019 | 0.013 | 0.671 | 0.970 | ||||
| G | r | — | 0.375 | −0.082 | −0.962 | — | — | 0.204 | −0.376 |
| p Value | 0.625 | 0.790 | 0.037 | 0.661 | 0.624 | ||||
| pT | r | — | 0.973 | 0.553 | −0.577 | — | — | 0.009 | −0.225 |
| p Value | 0.026 | 0.050 | 0.423 | 0.984 | 0.775 | ||||
| pN | r | — | 0.00 | 0.301 | – | — | — | −0.069 | — |
| p Value | 1.00 | 0.318 | 0.883 | ||||||
| Ki67 | r | — | 0.724 | −0.241 | −0.905 | — | — | −0.223 | 0.978 |
| p Value | 0.276 | 0.428 | 0.095 | 0.631 | 0.022 | ||||
ERα, oestrogen receptor α; G, tumour grade; IRS‐1, insulin receptor substrate 1; pN, lymph node involvement; pT, tumour size.
The associations between cytoplasmatic IRS‐1 and ERα positivity, G, pT, pN and the expression of the proliferation marker Ki67 were statistically analysed with the Pearson's correlation test. The statistically significant correlations given in bold. The absence of value is due to either the absence of samples in the group or to the homogeneity of samples (variance = 0); –, no samples analysed.