Fig. 5.
IRP2 expression in the hippocampus of elderly control and AD brains. No differences in the intensity or localization of IRP2 expression was seen in mild-moderate AD, severe AD, or DLB brains compared to controls. A) Cytoplasmic IRP2 expression in the CA1-2 hippocampal neurons in a severe AD patient (arrows); arrowheads show absence of staining in small glial cells (×200). B) Absence of IRP2 expression in the hippocampal dentate neurons (arrowhead) in a severe AD patient (×200). C) Absence of IRP2 expression in the hippocampal CA3 neurons (arrowhead) in a severe AD patient (×200). D) Absence of IRP2 expression in the ependymal cells (arrowhead) in a severe AD patient (×100). E) Cytoplasmic IRP2 expression in the CA4 hippocampal neurons (arrows) in an elderly control brain (×200).