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. Author manuscript; available in PMC: 2007 Aug 29.
Published in final edited form as: J Bone Miner Res. 2007 Jan;22(1):29–36. doi: 10.1359/JBMR.060914

FIG. 3.

FIG. 3.

PKR inhibitors antagonize 2-ME effects in osteosarcoma cells. (A) Cell survival. MG63 cells were treated with vehicle (Veh) and 5 µM 2-ME in the presence and absence of 25 µM SB 203580 or 50 µM of 2-AP for 72 h. Values are mean ± SE (N = 3 replicate cultures). *p ≤ 0.05 vs. Veh; #p ≤ 0.05 vs. 2-ME. (B) Hoechst dye staining. MG63 cells were treated with vehicle (Veh) and 5 µM of 2-ME in the presence and absence of 50 µM of 2-AP for 72 h. Values are mean ± SE (N = 3 replicate cultures). *p ≤ 0.05 vs. Veh; #p ≤ 0.07 vs. 2-ME.