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. 2007 Aug 16;104(35):13984–13989. doi: 10.1073/pnas.0705117104

Fig. 3.

Fig. 3.

The action of UVB on SOX9 is mediated through the cAMP pathway. (A) 35S labeling of a-LP NHM treated for 3 h with 20 μM forskolin or 21 mJ/cm2 UVB or untreated (Basal). Labeled proteins were immunoprecipitated with SOX9 or GAPDH antibodies. (B) UVB acts through the activation of PKA to up-regulate SOX9. 35S labeling of a-LP NHM without treatment (Basal) or with 21 mJ/cm2 UVB irradiation for 3 h with or without a PKA inhibitor (5 μM H89). Proteins were immunoprecipitated with antibodies against SOX9 and GAPDH.