Abstract
Significantly increased prevalences of particular HL-A antigens have been reported for many human diseases. The correlation is particularly striking in ankylosing spondylitis, Reiter's syndrome, psoriasis and some immunopathic disorders, so that HL-A typing may be of great value in diagnosis. The possible mechanisms whereby these associations may occur suggest the cause of certain disorders, and further investiatation will likely help in the understanding of the pathogenesis of many diseases.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bodmer W. F. Evolutionary significance of the HL-A system. Nature. 1972 May 19;237(5351):139–passim. doi: 10.1038/237139a0. [DOI] [PubMed] [Google Scholar]
- Brewerton D. A., Caffrey M., Nicholls A., Walters D., Oates J. K., James D. C. Reiter's disease and HL-A 27. Lancet. 1973 Nov 3;302(7836):996–998. doi: 10.1016/s0140-6736(73)91091-x. [DOI] [PubMed] [Google Scholar]
- Brewerton D. A., Hart F. D., Nicholls A., Caffrey M., James D. C., Sturrock R. D. Ankylosing spondylitis and HL-A 27. Lancet. 1973 Apr 28;1(7809):904–907. doi: 10.1016/s0140-6736(73)91360-3. [DOI] [PubMed] [Google Scholar]
- Clark D. A., Necheles T., Nathanson L., Silverman E. Apparent HL-A5 deficiency in malignant melanoma. Transplantation. 1973 Mar;15(3):326–328. doi: 10.1097/00007890-197303000-00010. [DOI] [PubMed] [Google Scholar]
- Eijsvoogel V. P., Du Bois R., Melief C. J., Zeylemaker W. P., Raat-Koning L., de Groot-Kooy L. Lymphocyte activation and destruction in vitro in relation to MLC and HL-A. Transplant Proc. 1973 Mar;5(1):415–420. [PubMed] [Google Scholar]
- Falchuk Z. M., Rogentine G. N., Strober W. Predominance of histocompatibility antigen HL-A8 in patients with gluten-sensitive enteropathy. J Clin Invest. 1972 Jun;51(6):1602–1605. doi: 10.1172/JCI106958. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Falk J. A., Fleischman J. L., Zabriskie J. B., Falk R. E. A study of HL-A antigen phenotype in rheumatic fever and rheumatic heart disease patients. Tissue Antigens. 1973;3(3):173–178. doi: 10.1111/j.1399-0039.1973.tb00991.x. [DOI] [PubMed] [Google Scholar]
- Feltkamp T. E., van den Berg-Loonen P. M., Nijenhuis L. E., Engelfriet C. P., van Rossum A. L., van Loghem J. J., Oosterhuis H. J. Myasthenia gravis, autoantibodies, and HL-A antigens. Br Med J. 1974 Jan 26;1(5899):131–133. doi: 10.1136/bmj.1.5899.131. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Grumet F. C., Coukell A., Bodmer J. G., Bodmer W. F., McDevitt H. O. Histocompatibility (HL-A) antigens associated with systemic lupus erythematosus. A possible genetic predisposition to disease. N Engl J Med. 1971 Jul 22;285(4):193–196. doi: 10.1056/NEJM197107222850403. [DOI] [PubMed] [Google Scholar]
- Mackay I. R., Morris P. J. Association of autoimmune active chronic hepatitis with HL-A1,8. Lancet. 1972 Oct 14;2(7781):793–795. doi: 10.1016/s0140-6736(72)92149-6. [DOI] [PubMed] [Google Scholar]
- Marsh D. G., Bias W. B., Hsu S. H., Goodfriend L. Association of the HL-A7 cross-reacting group with a specific reaginic antibody response in allergic man. Science. 1973 Feb 16;179(4074):691–693. doi: 10.1126/science.179.4074.691. [DOI] [PubMed] [Google Scholar]
- Morris R. I., Metzger A. L., Bluestone R., Terasaki P. I. HL-A-W27--a useful discriminator in the arthropathies of inflammatory bowel disease. N Engl J Med. 1974 May 16;290(20):1117–1119. doi: 10.1056/NEJM197405162902004. [DOI] [PubMed] [Google Scholar]
- Morris R., Metzger A. L., Bluestone R., Terasaki P. I. HL-A W27--a clue to the diagnosis and pathogenesis of Reiter's syndrome. N Engl J Med. 1974 Mar 7;290(10):554–556. doi: 10.1056/NEJM197403072901008. [DOI] [PubMed] [Google Scholar]
- Patel R., Mickey M. R., Terasaki P. I. Leucocyte antigens and disease. I. Association of HL-A2 and chronic glomerulonephritis. Br Med J. 1969 May 17;2(5654):424–426. doi: 10.1136/bmj.2.5654.424. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Russell A. S., Schlaut J., Percy J. S., Dossetor J. B. HL-A (transplantation) antigens in ankylosing spondylitis and Crohn's disease. J Rheumatol. 1974 Jun;1(2):203–209. [PubMed] [Google Scholar]
- Russell T. J., Schultes L. M., Kuban D. J. Histocompatibility (HL-A) antigens associated with psoriasis. N Engl J Med. 1972 Oct 12;287(15):738–740. doi: 10.1056/NEJM197210122871503. [DOI] [PubMed] [Google Scholar]
- Schlosstein L., Terasaki P. I., Bluestone R., Pearson C. M. High association of an HL-A antigen, W27, with ankylosing spondylitis. N Engl J Med. 1973 Apr 5;288(14):704–706. doi: 10.1056/NEJM197304052881403. [DOI] [PubMed] [Google Scholar]
- Snell G. D. The H-2 locus of the mouse: observations and speculations concerning its comparative genetics and its polymorphism. Folia Biol (Praha) 1968;14(5):335–358. [PubMed] [Google Scholar]
- Stokes P. L., Asquith P., Holmes G. K., Mackintosh P., Cooke W. T. Histocompatibility antigens associated with adult coeliac disease. Lancet. 1972 Jul 22;2(7769):162–164. doi: 10.1016/s0140-6736(72)91330-x. [DOI] [PubMed] [Google Scholar]
- Waters H., Konrad P., Walford R. L. The distribution of HL-A histocompatibility factors and genes in patients with systemic lupus erythematosus. Tissue Antigens. 1971;1(2):68–73. doi: 10.1111/j.1399-0039.1971.tb00080.x. [DOI] [PubMed] [Google Scholar]
- Zervas J. D., Delamore I. W., Israëls M. C. Leucocyte phenotypes in Hodgkin's disease. Lancet. 1970 Sep 26;2(7674):634–635. doi: 10.1016/s0140-6736(70)91400-5. [DOI] [PubMed] [Google Scholar]