Table 2.

Transfer of primed T cells: Kinetics of CTLp and of protection depended on time after transfer, route of infection, and irradiation of recipient

Treatment of recipient*	Time after transfer†	CTLp	Virus titer (log10 )		Survival LCMV i.c.¶
			LCMV i.v.‡	vacc-GP i.p.§
–	Control	<1:106	5.8 ± 0.1	5.9  ±  0.2	0/3
–	d  + 1	1:4  × 104	<2.3	1.1  ±  1.0	0/3
–	d  + 45	1:3  × 104	<2.3	5.8  ±  0.3	0/3
Irradiated	d  + 45	1:3  × 104	<2.3	<1	3/3

^*Mice were irradiated with 4.5 Gy. 

^†Spleen cells (3 × 10⁷) from LCMV-immune mice (day 100) were injected i.v.; control mice received spleen cells from unimmunized mice. 

^‡Mice were challenged i.v. with 200 pfu LCMV WE. 

^§Mice were challenged i.p. with 5 × 10⁶ pfu vacc-GP. 

^¶Mice were challenged i.c. with 30 pfu LCMV WE.