Figure 2.

Effects of recipient neutropenia or P-selectin blockade on hemodynamic and functional indices of lung preservation. Conditions are identical to those described in the legend to Fig. 1. After ligation of the native right pulmonary artery, measurements were recorded at the final time at which the recipient was alive or at 30 min if the animal survived to that time. (A) Pulmonary vascular resistance. (B) Pulmonary arterial flow. (C) Arterial oxygenation. Data are presented as the mean ± SEM. Controls, n = 8; NBα-PS, n = 5; α-P-selectin, n = 8; PMN(−), n = 6. ∗, P < 0.05 and ∗∗∗, P < 0.005 vs. Control; ‡, P < 0.05 vs. NBα-PS.