FIGURE 2. Serum IGF-I and IGFBP-3 decreased immediately after burn in both groups with significant difference between controls and oxandrolone. Serum GH was in the normal range immediately postburn, but started to decrease 2 to 7 days postburn. There was no difference between controls and oxandrolone. Serum estrogen (β-estradiol) and testosterone decreased in both groups postburn. Oxandrolone had no effect on serum β-estradiol, but significantly increased serum testosterone at various time points compared with controls. *Significant difference between controls versus oxandrolone, P < 0.05. Dashed lines represent upper and lower limit of the normal range.