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. 2007 Aug 31;3(8):e115. doi: 10.1371/journal.ppat.0030115

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© 2007 Pino et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Overview of select metabolic pathways of T. gondii taken into consideration in this study. Illustrated is the established (in black or blue) or putative (in red) localization of enzymes and pathways involved in (i) antioxidant defense and (ii) in the mitochondrial Krebs cycle and in similar metabolic reactions in the apicoplast. Blue, organelle-specific enzymes and pathways; red, enzymes and reactions whose subcellular localization is hypothetical. IRE, iron-responsive element; PRX, peroxiredoxin; PyC, pyruvate carboxylase; TLP, thioredoxin-like protein.