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. 2007 Aug 16;104(34):13804–13809. doi: 10.1073/pnas.0702753104

Fig. 4.

Fig. 4.

NE replacement in Dbh−/− mice partially restores motor coordination but exacerbates dyskinesias. Shown is the effect of NE replacement with DOPS + benserazide (labeled DOPS) on performance of Dbh−/− mice on challenging beam traversal (a), frequency of abnormal involuntary movements (b), time to orient down in the pole test (c), and time to descend in the pole test (d). Control, n = 36; Dbh−/−, n = 37; Dbh−/− given DOPS + benserazide, n = 7. *, P < 0.05 compared with control; ***, P < 0.001 compared with control; †, P < 0.05 compared with untreated Dbh−/−; ††, P < 0.01 compared with untreated Dbh−/− mice.