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Distribution of Rho A and Rac 1 is different in human epidermis. Skin was stained for Rho A (a), Rac 1 (c), or for F-actin (b and d) using ALEXA-phalloidin to visualize the entire epidermis. Rho A displayed membrane localization primarily in the deep epidermis (a), whereas Rac 1 was expressed predominantly in superficial epidermal layers (c). Bar = 50 μm.
