Skip to main content
. 2007 Sep;171(3):755–766. doi: 10.2353/ajpath.2007.061276

Figure 6.

Figure 6

Involvement of inflammatory cytokines, collagen, and TGF-β1. A–C: Blood samples were obtained from the vehicle- or M-CSF-treated mice at baseline, 24 hours, 3 days, and 7 days after the MI. Serum levels of IL-6 (A), MCP-1 (B), and IL-12p70 (C) were assessed. Data are represented as mean ± SEM (n = 5). D–F: Total RNA was extracted from the infarct (I) or noninfarct (NI) area in the sham-operated, vehicle-, and M-CSF-treated mice 14 days after the MI and analyzed for collagen type I, collagen type III, and TGF-β1 mRNA expression by real-time RT-PCR analysis. Results are expressed as mean ± SEM (n = 3). *P < 0.05, and **P < 0.01 versus sham.