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. 2007 Sep;171(3):976–992. doi: 10.2353/ajpath.2007.070345

Figure 4.

Figure 4

A–F: Gallyas silver staining on tissue section of the hippocampus and subiculum (A–C) and the spinal cord (D–F) of Tg30tau mice. A–C: Gallyas-positive neuronal inclusions are detected in the pyramidal layer and the subiculum in 3-month-old Tg30tau mice (A) and increase in number in 6-month-old (B) and 12-month-old (C) mice. D–F: Gallyas-positive neuronal inclusions are detected in neurons in the anterior horn of the spinal cord in 3-month-old Tg30 mice (D) and increase in number in 6-month-old (E) and 12-month-old (F) mice. G: Quantification of Gallyas-positive neuronal inclusions in cortex, hippocampal pyramidal layer, and lumbar gray matter of the spinal cord in 3-month-old (n = 6), 6-month-old (n = 5), and 12-month-old (n = 10) Tg30 tau mice, expressed as the mean number of Gallyas-positive profiles per tissue section. Scale bar = 15 μm.