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A schematic model for CadN’s function in R7 target selection. CadN mediates adhesive interactions between R7 growth cones and neurites of the medulla neurons during the first target selection stage. The CadN cytoplasmic domain interacts with α/β-catenins to regulate growth cone morphology. LAR and Liprin-α function in R7 growth cones, presumably to regulate actin-cytoskeleton for R7 target selection.
