Skip to main content
. 2003 Feb 15;17(4):443–448. doi: 10.1101/gad.1060703

Figure 1.

Figure 1

RNAi-mediated DNA instability in C. elegans. Strains that contain heat shock promoter-driven out-of-frame gfp-lacZ reporter gene fusions were assayed on dsRNA homologous to mlh-1, pms-2, msh-2, msh-6, M04F3.1, Y71F9AL.18 (pme-1), R06C7.7, and the empty vector control L4440. Two different out-of-frame constructs were tested, one containing a mononucleotide (A17) repeat placed immediately downstream of the ORF's ATG (this reporter has been used to screen the RNAi library), the other identical except that it lacks the mononucleotide repeat.