Table 1.
Microsatellite instability
| Marker
|
Wild type
|
Exol−/−
|
Mlhl−/−
|
|---|---|---|---|
| U12235 (A)n | 3% (7/244)a | 14% (11/79)b | 16% (12/73) |
| D7Mit91 (CA)n | 2% (3/124) | 0% (0/72)c | 15% (19/123) |
| D17Mit123 (CA)n | 6% (8/134) | 3% (2/68)d | 28% (19/69) |
a
Mutation frequency as determined by the number of unstable alleles divided by the total number of alleles scored.
b
Highly significant, p = 0.0007 versus wild type for marker U12235.
c
Not significant, p = 0.2992 versus wild type for marker D7Mit91.
d
Not significant, p = 0.5002 versus wild type for marker D17Mit123.