Table 2.
Genotype
|
Mutation rateb (×10−6)
|
Confidence limitsc (×10−6)
|
Fold increase
|
---|---|---|---|
WT | 0.02 | 0.0005–0.1 | 1 |
Exol−/− | 0.6 | 0.3–0.9 | 30 |
Msh2−/− | 3.0 | 2.4–3.7 | 150 |
Fluctuation analysis was performed as recently described (Abuin et al. 2000).
Mutation rates were determined according to calculations derived by Wierdl et al. 1996).
95% confidence interval for mutation rate (Dixon and Massey 1968).