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. 2003 Mar 1;17(5):603–614. doi: 10.1101/gad.1060603

Table 2.

Mutation rates at the Hprt locusa

Genotype
Mutation rateb (×10−6)
Confidence limitsc (×10−6)
Fold increase
WT 0.02 0.0005–0.1 1
Exol−/− 0.6 0.3–0.9 30
Msh2−/− 3.0 2.4–3.7 150
a

Fluctuation analysis was performed as recently described (Abuin et al. 2000). 

b

Mutation rates were determined according to calculations derived by Wierdl et al. 1996). 

c

95% confidence interval for mutation rate (Dixon and Massey 1968).