Figure 2.

Growth and differentiation of the hair follicle in K5/S33Yβ-catenin–ER mice treated daily with 4-OHT. A region of dorsal hair was clipped on both transgenic and wild-type littermates and the skin area was treated daily with 4-OHT in ethanol. Parasagittal sections of skin were taken at time points following initiation of treatment and stained with hematoxylin and eosin. Hair follicles in wild-type mice remained in the resting phase (telogen) throughout the experiment; growth and differentiation of transgenic hair follicles was dramatically stimulated.