Figure 2.

Reorganization of actin filaments in IAR-2 cells during formation of a new cell–cell contact. Shown are conventional epifluorescence micrographs of cells stained with the actin filament-specific probe, rhodamine–phalloidin. (A) Free edges of wounded IAR-2 monolayers contained prominent marginal bundles of actin filaments. (B) As an initial stable contact formed, marginal actin bundles at the site of the contact began to disassemble. (C) A concave arc-like bundle of actin filaments (arrow) was formed at the edge of the expanding contact. (Bar = 10 μm.)