Figure 5.

Bone-marrow-conditioned medium activates GPR105 altering GPR105⁺ cell function. (D) GPR105-transduced primary cord blood CD34⁺ cells transmigrate in response to conditioned medium from fetal bone marrow stroma. Data are represented as the mean chemotactic index and S.E.M. from six independent experiments with pretreatment conditions as indicated using GFP⁺ cells in each group. Comparison of chemotaxis with and without pretreatment with anti-GPR105 antibody is indicated with the p value following Student's t-test analysis.