Table 1.
Effect of treatment with BN/GRP antagonist RC-3095 on body and tumor weight and tumor volume in nude mice bearing xenografts of the human SCLC H-128 cell line
| Treatment | Tumor volume, mm3
|
Body weight, g | Tumor weight, mg | |
|---|---|---|---|---|
| Initial | Final | |||
| Control | 12.2 ± 0.8 | 275.7 ± 51.4 | 25.8 ± 2.1 | 290 ± 134 |
| RC-3095 | 12.9 ± 1.0 | 84.6 ± 21.1** | 24.5 ± 1.4 | 79 ± 51** |
, P < 0.01 vs. control.