Table 2.

Effect of treatment with BN/GRP antagonist RC-3095 on binding of BN and EGF in membranes of SCLC H-128 tumors

Treatment	BN		EGF
	Kd, nM	Bmax, fmol/mg protein	Kd, nM	Bmax, fmol/mg protein
Control	6.55  ±  0.93	512.8  ±  34.8	1.78  ±  0.26	216.8  ±  19.6
RC-3095	6.91  ±  0.22	228.9  ±  22.9**	0.86  ±  0.17*	52.9  ±  2.08**

Binding characteristics were obtained from 10-point displacement experiments. All values represent mean ± SE of 3-4 independent experiments, each done in duplicate or triplicate. 

^*, P < 0.05 vs. control. 

^**, P < 0.01 vs. control.