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Specificity of modulation of BK current by neurotrophic factors. (A) The BK current was augmented by 3 ng/ml NGF (N) (two out of six cells). The BK channel was blocked by 1 μM paxilline (P). (B-D) Neither 10 ng/ml CNTF (C), 50 ng/ml BDNF (B), nor 10 nM IGF-I (I) elicited any significant effect on the BK current in 3–5 experiments. (T = 3 mM TEA.)
