2.
Gender (Female) | Cohort (Age at Interview, y)a | Age of Onseta | |||||||
OR (95% CI) | P | 18–29, OR (95% CI) | 30–44, OR (95% CI) | P | Early (ages 18–29y), OR (95% CI) | Early Average (ages 30–44y), OR (95% CI) | Late Average (ages 45–65y) OR (95% CI) | P | |
Anxiety disorders | |||||||||
Panic disorder | 0.6 (0.2, 1.8) | .337 | 1.1 (0.3, 4.6) | 1.2 (0.3, 4.7) | .978 | 0.3* (0.1, 0.9)b | .025 | ||
Generalized anxiety disorder | 5.8 (0.8, 40.5) | .070 | 2.4 (0.4, 13.9)b | .318 | 0.2* (0.0, 0.7)b | 0.6 (0.1, 3.1) | .047 | ||
Specific phobia | 1.1 (0.5, 2.5) | .766 | 2.5 (0.8, 7.9) | 1.2 (0.6, 2.7) | .230 | 0.2* (0.1, 0.5)b | < .001 | ||
Social phobia | 0.6 (0.3, 1.1) | .096 | 4.3 (0.9, 19.3) b | .055 | 0.4* (0.1, 1.0)b | 1.1 (0.3, 3.3) | .046 | ||
Any anxiety disorders | 1.1 (0.7, 1.9) | .623 | 2.2* (1.1, 4.5) b | .024 | 0.2* (0.1, 0.2)b | < .001 | |||
Mood disorders | |||||||||
Major depressive episode | 1.5 (0.9, 2.5) | .078 | 1.8* (1.0, 3.4) | 1.3 (0.7, 2.2) | .105 | 0.4* (0.2, 0.8)b | 1.0 (0.5, 2.0) | < .001 | |
Dysthymia | 0.7 (0.3, 2.0) | .504 | 1.3 (0.4, 4.7) | 1.2 (0.4, 3.6) | .912 | 1.0 (0.3, 4.1) | 0.8 (0.2, 3.9) | 1.5 (0.3, 7.5) | .767 |
Bipolar disorder (broad) | 1.6 (0.5, 5.7) | .457 | 1.5 (0.2, 10.4) | 0.9 (0.2, 4.7) | .735 | 0.3* (0.1, 0.9) b | 1.0 | .030 | |
Any mood disorders | 1.6* (1.0, 2.4) | .033 | 1.7 (0.9, 3.3) | 1.3 (0.8, 2.4) | .244 | 0.3* (0.2, 0.6) | 0.5* (0.3, 0.9) | 0.9 (0.4, 1.7) | < .001 |
Substance use disorders | |||||||||
Alcohol abuse | 2.2 (0.7, 6.6) | .165 | 3.4* (1.1, 10.7) | 1.2 (0.4, 4.1) | .063 | 0.4 (0.2, 1.3) | 1.0 | 1.0 | .135 |
Alcohol abuse with dependence | 1.2 (0.2, 9.7) | .840 | 4.0 (0.4, 37.2) | 1.1 (0.3, 3.8) | .444 | 0.9 (0.0, 23.2) | 0.7 (0.1, 9.9) | 2.5 (0.3, 17.8) | .393 |
Drug abusec | . . . | . . . | 0.1* (0.0, 0.9) | 0.1* (0.0, 0.5) | .012 | 1.2 (0.2, 7.7) | 0.7 (0.2, 2.8) | 1.0 (0.2, 4.3) | .892 |
Any substance-use disorders | 2.3 (0.7, 7.9) | .159 | 2.4 (0.8, 7.3) | 1.2 (0.4, 3.6) | .257 | 1.1 (0.3, 4.4) | 1.9 (0.4, 8.1) | 1.9 (0.6, 5.8) | .568 |
Note. OR = odds ratio; CI = confidence interval. We assessed mental and substsance use disorders as defined by the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition14 with version 3.0 of the WHO Composite International Diagnostic Interview, a fully structured, lay-administered diagnostic questionnaire used in face-to-face interviews.15 Drug abuse with dependence disorder category was omitted because of insufficient lifetime cases (n < 30) but included in the “any substance-use disorders” category.
aReference category is age 45–65 years.
bGroups in this row were collapsed.
cGender was used as a control variable in the model except for drug abuse (because of insufficient cases of women).
*Significant at the 0.05 level in a 2-sided test.