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8-Br-cGMP and MY-5445 increase the expression of GFAP in mouse primary astrocytes. Cells were stimulated with either different concentrations of 8-Br-cGMP (A, B) or MY-5445 (C, D) under serum-free condition. After 24 h of stimulation, the expression of GFAP was analyzed in cells by semiquantitative RT-PCR. Results are mean ± SD of three different experiments. ap < 0.001 versus control.
