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. 2006 Oct;88(6):525–529. doi: 10.1308/003588406X117106

Table 1.

Pro- and anti-angiogenic agents4,17

Angiostimulators Angio-inhibitors
Vascular endothelial growth factor (VEGF) Thrombospondins-1, -2
Basic and acidic fibroblast growth factors (bFGF, aFGF) Endostatin
Platelet-derived endothelial cell growth factor Angiostatin
Matrix metalloproteinases (MMPs) Interferons α and β
Insulin-like growth factor (IGF) Interleukin-12 (IL-12)
Epidermal growth factor (EGF) Tamoxifen
IL-1, IL-4, IL-6, IL-8, IL-15 Thalidomide
Angiogenin Captopril
Integrins αv1β3 and αv1β5 Dexamethasone
Endotoxin Indomethacin
Endothelin-1 Diclofenac
Angiopoietin-1 (Ang-1) Angiopoietin-2 (Ang-2)
Tumour necrosis factor (TNF)-α (in vivo) TNF-α (in vitro)