Figure 2.

Distribution of coiled coil likelihoods for 168 histidine kinase sequences. The likelihoods are for the kinase region directly preceding the H block. (A) Three prediction methods are compared: learncoil (24) using the final probabilities obtained as described in Methods (black), paircoil (18) (white), and newcoils (17) (gray). (B) Comparison of normalized learncoil likelihood distributions for the entire histidine kinase test set (168 sequences, black), a subset run separately as described in Methods (142 sequences, horizontal stripes), and the sequences excluded from the subset (26 sequences, diagonal stripes).