Figure 3.

Comparison of singles frequencies (see Methods) for the 20 amino acids before and after learncoil iteration (original frequency and final average frequency, respectively). A diagonal line is indicated for clarity. (A) Amino acid content at all heptad positions. Points for histidine and for the more abundant amino acids (frequency >5%) are labeled. (B) Amino acid composition of position g. Points are labeled for amino acids whose frequency changes most noticeably. (C) Amino acid composition of the hydrophobic interior positions a (filled squares) and d (open squares). Points for the more abundant amino acids are labeled.