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. 1998 Mar 17;95(6):2761–2766. doi: 10.1073/pnas.95.6.2761

Figure 4.

Figure 4

(A) Nucleotide sequence and predicted amino acid sequence of the Met ORF, derived from sequence determination of 3.3-kb cDNA clones. The bHLH domain is underlined, the PAS-A domain is boldly underlined, and the PAS-B domain is double underlined. Single-letter abbreviations for the amino acid residues are: A, Ala; C, Cys; D, Asp; E, Glu; F, Phe; G, Gly; H, His; I, Ile; K, Lys; L, Leu; M, Met; N, Asn; P, Pro; Q, Gln; R, Arg; S, Ser; T, Thr; V, Val; W, Trp; and Y, Tyr. (B) Amino acid sequence alignment of the homologous regions for the bHLH, PAS-A, and PAS-B domains of MET with those of human AHR and ARNT. Number in parenthesis indicates the position of the initial amino acid of each domain in the respective protein. Identical sequences are boxed.