Table 2.
Expression of PP2Aas inhibits encystation and excystation compared to the wild type and irrelevant transfected C6 controls.
| C6 | transfected C6b | PP2Aasc | |
|---|---|---|---|
| ESV/ 50 trophozoites | 104.0 ± 33.8 | 160.3 ± 53.5 | 19.3 ± 8.3 |
| ESV/positivea trophozoite | 3.0 ± 0.3 | 5.1 ± 2.2 | 1.1 ± 0.8 |
| % positivea trophozoites | 55.7 ± 12.0 | 56.6 ± 1.5 | 26.3 ± 7.5 |
| Number of cysts/ml | 25.2 ± 5.7 × 104 | 22.4 ± 9.3 × 104 | 6.1 ± 3.3 × 104 |
| Excyzoites/ml | 966.6 ± 208.2 | 755.7 ± 72.6 | 66.6 ± 115.5 |
a
Having one or more ESV
b
data are an average of three independent transformed C6 cell lines (orf ID: 4018, 3582, 4689; ORF ID numbers can be used to view the data on GiardiaDB(www.mbl.edu/Giardia),
c
significantly different from the C6 controls as tested with the T‐test, with a p‐value <0.05.