Figure 8.
Two pathways for the recruitment of the RENT complex to rDNA. Fob1 recruits the RENT complex to the replication fork block region of NTS1. Silent chromatin generated by RENT then inhibits Fob1-dependent recombination. A Fob1-independent pathway, involving Pol I, recruits RENT to the NTS2/18S region. See text for details. Labels are as in Figure 1.