Table 1.
Functional classification of dE2F-regulated genes
| Function/Group | A | B | C | D | E | T |
|---|---|---|---|---|---|---|
| S phase | 3 | 0 | 0 | 0 | 0 | 3 |
| DNA replication | 16 | 12 | 0 | 0 | 0 | 28 |
| DNA repair | 2 | 7 | 0 | 0 | 0 | 9 |
| Chromatin | 8 | 3 | 0 | 0 | 0 | 11 |
| Mitosis | 9 | 4 | 2 | 0 | 0 | 15 |
| Differentiation | 0 | 0 | 0 | 1 | 7 | 8a |
| Unknown/other | 29 | 17 | 8 | 14 | 14 | 82 |
Number of genes per class of E2F regulated genes encoding various biological functions. (A-E) Classes of E2F regulated genes. (T) Total number of genes for each function.
a
4/8 function during oogenesis, 1/8 during germ line formation, 3/8 are male-specific as demonstrated in this study (Fig. 6).