Figure 5.
The sorting motifs of the furin cytoplasmic domain. Shown is the sequence of the human furin cytoplasmic domain. The various intracellular sorting motifs are indicated. See text for more details. ABP, actin-binding protein; AP, adaptor protein; CK2, casein kinase 2; PACS-1, phosphofurin acidic cluster sorting protein-1; PP2A, protein phosphatase 2A; TGN, trans-Golgi network. For a key to furin domain organization, see FIG. 1.