Table 3.
Measures of central tendency for half-life of serum elimination for PFOS, PFHS, and PFOA for 26 retired fluorochemical production workers.
| Days
|
Years
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Fluorochemical | Arithmetic mean (95% CI) | GM (95% CI) | Median | Range | Arithmetic mean (95% CI) | GM (95% CI) | Median | Range |
| PFOS | 1,976a (1,434–2,517) | 1,751 (1,461–2,099) | 1,661 | 885–7,919 | 5.4a (3.9–6.9) | 4.8 (4.0–5.8) | 4.6 | 2.4–21.7 |
| PFHS | 3,109b (2,348–3,870) | 2,662 (2,112–3,355) | 2,586 | 798–9,858 | 8.5b (6.4–10.6) | 7.3 (5.8–9.2) | 7.1 | 2.2–27.0 |
| PFOA | 1,378 (1,131–1,625) | 1,273 (1,083–1,495) | 1,257 | 561–3,334 | 3.8 (3.1–4.4) | 3.5 (3.0–4.1) | 3.4 | 1.5–9.1 |
GM, geometric mean.
a
If subject 19 is excluded as a potential high outlier for PFOS (Figure 2), the arithmetic mean half-life = 1,738 days (95% CI, 1,497–1,979) or 4.8 years (95% CI, 4.1–5.4).
b
If subject 24 is excluded as potential high outlier for PFHS (Figure 2), the arithmetic mean half-life = 2,839 days (95% CI, 2,297–3,381) or 7.8 years (95% CI, 6.3–9.3).