Table 5.

Difference in length of intensive care unit stay between the three study periods in severity subgroups of the study population

Subgroup and outcome	Pre-protocol	Transition	Protocol
High severity of illness
ICU length of stay, days, median (IQR)	2.4 (1.13–5.02)	2.06 (1.05–4.64)*	2.4 (1.21–4.71)
28–day ICU free days, median (IQR)	23.2 (0.0–26.2)	24.1 (0.0–26.4) *	24.4 (0.0–26.3)*
Low severity of illness
ICU length of stay, days, median (IQR)	1.0 (0.75–1.99)	1.0 (0.72–1.93)	1.1 (0.77–1.99)
28-day ICU free days, median (IQR)	26.9 (25.9–27.3)	26.9 (26.0–27.3)	26.9 (25.9–27.2)

*P value < 0.05 compared to the pre-protocol period; ICU = intensive care unit; IQR = interquartile range; SD = standard deviation