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. 2007 Jun 11;104(25):10364–10369. doi: 10.1073/pnas.0701622104

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© 2007 by The National Academy of Sciences of the USA

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Fig. 3. — Identification and analysis of Rad53-dependent phosphorylation. (A) Number and percentage (related to total number of Mec1/Tel1-dependent phosphorylation identified) of Rad53-dependent phosphorylation identified. All Rad53-dependent phosphorylation was also Mec1/Tel1-dependent (n = 62). (B) Frequency of amino acids at the +1 position of phosphorylated serine or threonine for Rad53-independent and Mec1/Tel1-dependent phosphorylation (black bars) and Rad53-dependent phosphorylation (gray bars). (C) Simplified representation of the Mec1, Tel1, and Rad53 kinases and their targets in the DNA damage response.