Table 2.

S. tropica CNB-440 secondary metabolite biosynthetic gene clusters

Cluster designation	Actual (*) or predicted product	Type	%G+C	Size, kb	Gene cluster location
pks1	10-membered enediyne	Enediyne PKS	67	30	Stro0586–0610
pks2	Glycosylated decaketide	Type II PKS	69	35	Stro2204–2235
pks3	Spore pigment	Type II PKS	71	23	Stro2486–2509
spo	Sporolide*	Enediyne PKS	68	50	Stro2695–2733
slm	Salinilactam*	Type I PKS	70	80	Stro2757–2781
pks4	Aromatic polyketide	Type III PKS	73	10	Stro4262–4271
nrps1	Unknown dipeptide	NRPS	68	31	Stro0672–0699
nrps2	Reductively offloaded tetrapeptide	NRPS	70	33	Stro4409–4429
sal	Salinosporamide*	PKS–NRPS	67	41	Stro1012–1043
lym	Lymphostin*	PKS–NRPS	71	33	Stro3042–3066
sid1	Desferrioxamine-like siderophore	NRPS-independent	72	18	Stro2539–2554
sid2	Yersiniabactin-like siderophore	PKS–NRPS	71	28	Stro2636–2660
sid3	Unknown siderophore	PKS–NRPS	72	30	Stro2786–2813
sid4	″Coelibactin″-like siderophore	NRPS	70	44	Stro2814–2842
amc	Unknown aminocyclitol	Aminocyclitol	70	8	Stro2340–2346
terp1	Unknown terpene	Terpene	72	10	Stro3244–3253
terp2	Unknown carotenoid	Terpene	70	12	Stro4437–4445