Fig. 2.
Reproductive system defects in female Kiss1tm1PTL-null mice. (A) Reduced ovary size and thread-like uterus in mutant mice. (Scale bar: 1 mm.) (B and C) Histology of ovaries showing larger number of atretic follicles (arrows) in mutant mice (C) and absence of late-stage follicle maturation (f) present in wild-type mice. (Scale bars: 100 μm.) (D and E) Histology of uterus showing full development of glands (arrows) in the endometrial layer in wild type (D) in contrast to mutant mice (E). L, uterine lumen. (Scale bars: 25 μm.)