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. Author manuscript; available in PMC: 2008 Apr 30.
Published in final edited form as: Dev Cell. 2007 May;12(5):699–712. doi: 10.1016/j.devcel.2007.03.014

Fig. 3. Downregulation of GEF-H1 causes mitotic aberrations.

Fig. 3

Distribution of mitotic phenotypes in GEF-H1 (GEF-H1 siRNA) or control siRNA (CTRL siRNA)-transfected cells. Classification of phenotypes: a) regular cytokinesis; b) collapsing: cortical hyperactivity during metaphase, finally collapsing; c) instability: membranous aberrations around the CF w/o impairment of cytokinesis; d) failed cytokinesis: membranous aberrations during cytokinesis that are not compensated and gave rise to cytokinesis failure. Values are given as percentage of total cells with error bars indicating ± SEM. Actual numbers are indicated. In four independent experiments, a total of 144 GEF-H1-depleted and 114 control-depleted cells were scored (*≤ 0.05; **≤ 0.005; *** ≤0.0005).