Table 2.
Binding parameters of 1251-[Tyr11]somatostatin 14 binding to sst2 in transfected COS-7 cells
| Kd (nM) | Bmax (pmol/106cells) | |
|---|---|---|
| sst2 | 1.71 ± 0.79 | 0.52 ± 0.09 |
| Y228F | 8.72 ± 2.89* | 1.33 ± 0.33* |
| Y312F | 4.13 ± 1.92 | 0.9 ± 0.39 |
| Y228/312F | 3.43 ± 0.4 | 0.56 ± 0.16 |
Data represent mean ± SE obtained from three separate experiments performed in duplicate.