Figure 5.

Choice performance across serial reversals of the final odor discrimination problem (D4) by OFC-lesioned (black bars) and control (white bars) rats. Performance is shown for both the retention and reversal phases of training, represented as the trials required for each rat to meet a criterion of 18 correct responses in a moving block of 20 trials. Gray areas on reversal days indicate the trials required to reach 50% performance as a measure of perseveration on the old contingencies. OFC-lesioned rats were impaired at acquiring reversals, irrespective of whether the reversed odor discrimination problem was composed of new contingencies (S1−/S2+) or was a return to the original contingencies (S1+/S2−). There was no effect of lesion on the tendency to perseverate on reversal days.