Table 1.
Quantitative analysis of normal and tumor centrosomes
A Tissue | Analysis of centrin staining volume
|
|||
---|---|---|---|---|
Mean μm3 (SD) | Vol. per cell μm3 (SD) | n spots per cell (SD) | n | |
Normal | 0.013 (0.004) | 0.011 (0.002) | 1.5 (0.3) | 327 |
Tumor | 0.114 (0.022) | 0.492 (0.209) | 4.3 (1.2) | 1283 |
B Tissue | Analysis of centriole profiles per thin section
|
||
---|---|---|---|
Mean | Range | n | |
Normal | 0.061 | 0–2 | 115 |
Tumor | 0.63 | 0–5 | 111 |
C Tissue | Microtubules nucleated per cell, n
|
|||
---|---|---|---|---|
Median | Mean number | Range | n | |
Normal | 1 | 4.8 | 0–52 | 150 |
Tumor | 39.7 | 47.1 | 0–270 | 150 |