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Role of TLR3 or PKR induced by IFN-α/β in poly(I:C)-stimulated DCs. (a) WT, TLR3–/–, or PKR–/– DCs were stimulated with poly(I:C) or LPS for 24 h and analyzed as in Fig. 1a.(b) Real-time RT-PCR analysis of indicated cytokine mRNAs after poly(I:C) stimulation in WT, TLR3–/–, or PKR–/– DCs.
