. 2003 Aug 20;100(19):10942–10947. doi: 10.1073/pnas.1731272100

Table 2. CN CFUs in the lungs and the brains of A/JCr mice i.v. infected with 10⁵ CN organisms and treated with ¹⁸⁸Re-18B7 mAb 24 h after infection.

	No. of cfu/g of tissue, × 10⁴
Organ	Untreated mice and treated with unlabeled 18B7, 50 μg	50 μCi of ¹⁸⁸Re-18B7	100 μCi of ¹⁸⁸Re-18B7	200 μCi of ¹⁸⁸Re-18B7
Lungs	550 (47)^*	41 (6) (P = 0.001)	21 (5) (P = 0.001)	3.3 (2) (P = 0.001)
Brains	11 (5)	0.10 (0.05) (P < 0.001)	0.8 (0.1) (P = 0.002)	1.1 (0.1) (P = 0.002)

Mice were killed 48 h after the treatment with ¹⁸⁸Re-18B7 (¹⁸⁸Re; t_1/2 = 2.8 d); the colony counts for 100 and 10 times dilutions for the lungs and brains, respectively, are given. Numbers in parentheses are SD.

P values were calculated by the Wilcoxon test, and the groups treated with ¹⁸⁸Re-18B7 were compared with the combined group of untreated mice and those treated with unlabeled 18B7 mAb.

Table 2. CN CFUs in the lungs and the brains of A/JCr mice i.v. infected with 105 CN organisms and treated with 188Re-18B7 mAb 24 h after infection.

Table 2. CN CFUs in the lungs and the brains of A/JCr mice i.v. infected with 10⁵ CN organisms and treated with ¹⁸⁸Re-18B7 mAb 24 h after infection.