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. 2003 Sep 2;100(19):11098–11103. doi: 10.1073/pnas.1834060100

Table 1. Effect of indomethacin on serum phosphate and urinary phosphate excretion in C57/B6 and Hyp mice.

Mice Treatment Serum creatinine, mg/dl Serum phosphate, mg/dl Urine creatinine, mg/dl Urine phosphate, mg/dl FEPO4, %
C57/B6 Vehicle 0.2 ± 0.1 7.2 ± 0.4 30 ± 5 25.7 ± 12.0 2.7 ± 1.2
C57/B6 Indomethacin 0.3 ± 0.1 8.0 ± 0.4 40 ± 3 15.1 ± 5.7 2.6 ± 0.6
Hyp Vehicle 0.2 ± 0.1 2.9 ± 0.2* 47 ± 6 80.3 ± 32.5 13.0 ± 3.2*
Hyp Indomethacin 0.2 ± 0.2 4.1 ± 0.2 47 ± 6 22.5 ± 11.4 2.2 ± 1.1

In all cases, n ≥ 6

*

, P < 0.05 vs. other groups

, P < 0.05 vs. C57/B6, C57/B6 indomethacin, and Hyp vehicle